Huvudansvarig är Per Kristiansson.
Nedan presenteras ett urval av projekt på engelska.
Uppsala Pelvic Pain Study (UPPS)
The focus of this prospective cohort study is the patho-physiologic process explaining how apparently healthy and well-trained young women within a few months of pregnancy can become severely disabled by pregnancy induced low back and pelvic pain that may persist for several years after delivery. We hypothesize that a functionally disturbed remodelling and repair of ligaments of the lowest back will be involved in the process. The study is a population-based cohort study of women with baseline assessment before gestational week 12 and additional assessments at gestational week 36 and 6 months after childbirth. Individual patient data are collected by means of web-based questionnaires, clinical examination and blood tests. General joint mobility, skin extensibility and biochemical markers, as a measure of fragile connective tissue, will be measured thoroughly as well as the outcome measures low back pain location and back pain provocation tests. The studies started in 2014. The project has financial support from Regionala Forskningsrådet in the Uppsala-Örebro region and Uppsala County Council.
Pelvic pain during pregnancy and hormonal contraceptive use
The project was the results of collaboration with researchers involved in the Norwegian Mother and Child Cohort. The study results suggest an exogenous hormonal influence on the development of pregnancy induced pelvic pain as the reported use of progestine hormonal contraceptive was associated with a higher degree of pregnancy induced pelvic pain. An ongoing study evaluates the effect of hormonal contraceptive use and pelvic pain persisting after childbirth.
Laser therapy of pregnancy induced back and pelvic pain persistent after childbirth
The aim of the study is to evaluate the short and long term effect of low level laser therapy in women with pregnancy-induced chronic pelvic pain regarding functioning and pain relief in a prospective triple-blinded randomized controlled trial. The laser treatment will be applied to the sacral back by a standard laser head and to the internal pelvis by a transvaginal probe. The study includes a 4 weeks treatment session with either active or sham treatment with follow-up immediately and 6 months after end of treatment. This is a collaboration between physiotherapists, gynecologist, general practitioner and laser manufacturer. The project has financial support from Uppsala and Västernorrland County Councils.
Sexual and reproductive health among young men
The overall aim of the study is to investigate present conditions and room of improvement for sexual and reproductive health within the primary health care of young men. The study assesses sexual and reproductive health among young men in Sweden, describes the notion of sexual and reproductive health among young men and among staff of primary health care and analyze time for yourself under confidentiality with a physician, The study is receiving financial support from the Primary Health Care of Sörmland County Council and Uppsala University.